A method for model-free partial volume correction in oncological PET
نویسندگان
چکیده
منابع مشابه
A method for model-free partial volume correction in oncological PET
UNLABELLED BACKGROUND As is well known, limited spatial resolution leads to partial volume effects (PVE) and consequently to limited signal recovery. Determination of the mean activity concentration of a target structure is thus compromised even at target sizes much larger than the reconstructed spatial resolution. This leads to serious size-dependent underestimates of true signal intensity ...
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We have developed, optimized, and validated a method for partial volume effect (PVE) correction of oncological lesions in positron emission tomography (PET) clinical studies, based on recovery coefficients (RC) and on PET measurements of lesion-to-background ratio (L/B m) and of lesion metabolic volume. An operator-independent technique, based on an optimised threshold of the maximum lesion upt...
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Accurate quantification of tracer uptake in small tumors using PET is hampered by the partial-volume effect as well as by the method of volume-of-interest (VOI) delineation. This study aimed to investigate the effect of partial-volume correction (PVC) combined with several VOI methods on the accuracy and precision of quantitative PET. METHODS Four image-based PVC methods and resolution modeli...
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ژورنال
عنوان ژورنال: EJNMMI Research
سال: 2012
ISSN: 2191-219X
DOI: 10.1186/2191-219x-2-16